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Objectives: This study aimed to identify factors influencing work retention among general hospital nurses. Methods: Data were collected from 208 nurses working at a general hospital in Busan from December 9, 2021, to February 9, 2022. Data were analyzed using SPSS 26.0. Results: Job esteem (β =.278, p<.001), natural emotional expression (β=.177, p=.005), very dissatisfied with salary (β=-.213, p<.001), working in the desired department (β=.125, p=.033) and age (β=.239, p<.001) influenced the work retention. However, the nursing work environment did not influence work retention. Conclusions: To improve nurses’ intentions to continue working in general hospitals, it is necessary to inspire job respect, reduce emotional labor through training, express feelings in a healthy way, and pay an appropriate salary.