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원문정보

Identification Mitragynine and Its Metabolites in Urine to Detect Kratom Use

박동은, 우상희, 김동우

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초록

영어

Kratom is the leaves of Mitragyna speciosa, which is native to Southeast Asia, and is increasingly used for recreational and therapeutic purposes without medical supervision. Due to its indole alkaloid components, such as mitragynine and 7-hydroxymitragynine, it causes stimulating effects at low doses and opioid-like actions at high doses, and may exhibit various side effects that can lead to death when taken in an overdose and combined with other drugs, and thus it is considered to be regulated. In this case, kratom was seized from a Thai man, and his urine was commissioned to confirm whether he was taking kratom. Mitragynine, 7-hydroxymitragynine, 9-O-demethylmitragynine and 16-carboxymitragynine were detected in urine using liquid-liquid-extraction and LC-QTOF-MS.

목차

Abstract
Ⅰ. 서론
Ⅱ. 사건 개요
Ⅲ. 재료 및 방법
1. 시약 및 재료
2. 시료전처리 방법
3. 분석기기 및 조건
Ⅳ. 실험결과 및 고찰
Ⅴ. 사사
Ⅵ. 참고문헌

저자정보

  • 박동은 Dongeun Park. 국립과학수사연구원 독성학과 감정관
  • 우상희 Sanghee Woo. 대전과학수사연구소 독성화학과 감정관
  • 김동우 Dongwoo Kim. 대전과학수사연구소 독성화학과 감정관

참고문헌

자료제공 : 네이버학술정보

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