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Review

Internal Dosimetry: State of the Art and Research Needed

원문정보

Francois Paquet

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초록

영어

Internal dosimetry is a discipline which brings together a set of knowledge, tools and procedures for calculating the dose received after incorporation of radionuclides into the body. Several steps are necessary to calculate the committed effective dose (CED) for workers or members of the public. Each step uses the best available knowledge in the field of radionuclide biokinetics, energy deposition in organs and tissues, the efficiency of radiation to cause a stochastic effect, or in the contributions of individual organs and tissues to overall detriment from radiation. In all these fields, knowledge is abundant and supported by many works initiated several decades ago. That makes the CED a very robust quantity, representing exposure for reference persons in reference situation of exposure and to be used for optimization and assessment of compliance with dose limits. However, the CED suffers from certain limitations, accepted by the International Commission on Radiological Protection (ICRP) for reasons of simplification. Some of its limitations deserve to be overcome and the ICRP is continuously working on this. Beyond the efforts to make the CED an even more reliable and precise tool, there is an increasing demand for personalized dosimetry, particularly in the medical field. To respond to this demand, currently available tools in dosimetry can be adjusted. However, this would require coupling these efforts with a better assessment of the individual risk, which would then have to consider the physiology of the persons concerned but also their lifestyle and medical history. Dosimetry and risk assessment are closely linked and can only be developed in parallel. This paper presents the state of the art of internal dosimetry knowledge and the limitations to be overcome both to make the CED more precise and to develop other dosimetric quantities, which would make it possible to better approximate the individual dose.

목차

ABSTRACT
Introduction
Methods for Determining Doses After Internal Contamination
State of the Art
1. Biokinetic Models
2. Retention and Excretion Functions for Bioassay Interpretation
3. Calculation of Nuclear Transformations and Energy Emitted in Organs and Tissues
4. Use of Numerical Phantoms and Codes for Radiation Transport
5. Radiation and Tissue Weighting Factors
6. Conclusions on the State of the Art
Gaps That Would Need Improvements
1. Towards More Accurate Determination of the CED for the Reference Person
2. Towards an Individualized Assessment of the Dose Received by Individuals
Conclusion
Conflict of Interest
Acknowledgements
References

저자정보

  • Francois Paquet Institut de Radioprotection et de Sûreté Nucléaire IRSN/PSE-ENV/SEREN, Saint Paul Lez Durance, France

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