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사례보고

테트라민 중독 사망사례 분석

원문정보

Characterizations of Death by the Tetramine Poisoning

이상기, 정희선, 김재욱, 이호선, 이희상

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

Tetramethylammonium(TMA, tetramine) is a toxic quaternary ammonium compound, consisting of four methyl groups attached to a central nitrogen atom. TMA has been detected in a number of marine organism that are eaten by humans. In the past, most cases of TMA intoxication have occurred through eating seafood containing TMA, such as carnivorous gastropods. Nowadays, TMA hydroxide(TMAH) that decomposes to produce TMA is used widely in the manufacture of semiconductors and liquid crystal displays (LCDs). As a result, the case of TMA intoxication is increasing. TMA acts directly on nicotinic and muscarinic receptors that are responsible for depolarization and, at high doses, blockage of depolarization. TMA may cause nausea, vomiting, headache, impaired vision, temporary blindness, salivation, lacrimation, fasciculation and convulsion and motor paralysis. The symptoms of TMA intoxication generally are mild and transient because of rapid elimination of TMA from the body. However, in severe cases, paralysis of the respiratory muscles can occur and this causes death. In this study, we analyzed TMA in femoral blood, heart blood and gastric contents of victim. The concentrations of TMA in femoral blood and heart blood were 7.95 mg/L and 13.1 mg/L, respectively. This case can be considered as a good reference when studying the relationship between TMA-induced death and blood concentration.

목차

Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
1. 사건개요
2. 약물 분석
3. 테트라민 분석
Ⅲ. 결과 및 고찰
Ⅳ. 참고문헌

저자정보

  • 이상기 Sangki Lee. 성균관대학교 과학수사학과 연구원, 교수
  • 정희선 Heesun Chung. 성균관대학교 과학수사학과 연구원, 교수
  • 김재욱 Jaeook Kim. 대구과학수사연구소 독성화학과 감정관
  • 이호선 Ho-Sun Lee. 대구과학수사연구소 독성화학과 감정관
  • 이희상 Heesang Lee. 대구과학수사연구소 독성화학과 감정관

참고문헌

자료제공 : 네이버학술정보

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