원문정보
초록
영어
Genus of Rhododendron has been used in traditional medicine since ancient times and is known to be effective in immune function, inflammation, and cold symptoms. And the reason for this activity is the flavanonol type among flavonoids in the genus of Rhododendron. Among the flavanonol types, Taxifolin-3-O-arabinopyranoside was isolated from the root of native R. mucronulatum in Korea, and the structure was finally identified through HPLC, LC-MS/MS, 1H-NMR, and 13C-NMR. Taxifolin-3-O-arabinopyranoside is a compound mainly found in R. mucronulatum, a representative species of the genus of Rhododendron, and exhibits antioxidant, anti-inflammatory, and anti-atopic activities. In this study, Taxifolin-3-O-arabinopyranoside was chemotaxonomic significant in 5 species of the genus Rhododendron native to Korea (R. mucronulatum, R. mucronulatum var. ciliatum, R. schlippenbachii, R. yedoense var. Poukhanense, R. japonicum for. Flavum). Compared with the existing literature, Taxifolin-3-O-arabinopyranoside was identified for the first time in 4 species of Rhododendron except for the R. mucronulatum.
목차
Introduction
Materials and Methods
Plant extracts of Rhododendron species
Separation of active compounds in the root of R.mucronulatum
Structural identification of active compound isolated from an extract of the root of R. mucronulatum
Quantitative analysis of Taxifolin-3-O-arabinopyranoside using HPLC of several species of the genus of Rhododendron
Molecular weight confirmation using LC-MS/MS of several species of the genus of Rhododendron
Results and Discussion
Conclusion
Acknowledgements
References