earticle

영어

This study was conducted to investigate the effect of hair growth by oral administration of extracts classified into high and low concentrations to experimental animals. Before proceeding with the animal experiment, the antioxidant activity capacity of kelp, lavender, and kelp was measured and the experiment was conducted. Antioxidation experiments were performed by measuring DPPH radical scavenging ability, measuring nitrite scavenging ability, measuring total flavonoid content, and measuring total polyphenol content. The higher the concentration, the higher the antioxidant capacity. The DPPH production inhibitory effect was found in kelp, nitrite inhibitory effect in lavender, total flavonoid content in dolbean, and total polyphenol content in lavender. The extract was orally administered to experimental animals once a day, and hair length was measured once a week, and hair density was measured on the second week. A higher value was measured in the experimental animal group to which the extract was administered when compared with the control group. High-concentration lavender had the longest hair length, and high-concentration kelp showed the highest hair density. The weight of the experimental animal group was higher than that of the control group, and the highest value was measured in the high concentration of lavender. The liver and heart were measured for organ weights in the experimental group, and the highest value was measured in high concentration lavender. From the results, it was confirmed that the antioxidants of kohlrabi, lavender, and kelp are effective in antioxidant function and hair growth.

한국어

본 연구는 고농도와 저농도로 구분한 추출물을 실험동물에 경구투여하여 모발 성장의 효과 여부를 알아 보기 위해 진행하였다. 동물실험을 진행하기 전 종지나물, 라벤더, 다시마의 항산화 활성능력을 측정하고 실험을 진행하였다. 항산화 실험은 DPPH radical 소거능 측정, 아질산염 소거능력 측정, 총 플라보노이드 함량 측정, 총 폴리페놀 함량 측정하였다. 높은 농도일수록 항산화 능력이 증가하였으며 DPPH 생성 억제효과에선 다시마, 아질 산염 억제효과에선 라벤더, 총 플라보노이드 함량은 종지나물, 총 폴리페놀 함량은 라벤더에서 높은 값을 나타내 었다. 실험동물에게 추출물을 하루에 한 번 경구투여하여 일주일에 한번 모발의 길이를 측정하고 2주차가 되는 날 모발의 밀도를 측정하였다. 대조군과 비교했을 때 추출물을 투여한 실험동물군에서 높은 값을 측정하였다. 고농도 라벤더에서 모발의 길이가 가장 길었으며 고농도 다시마에서 가장 높은 모발의 밀도를 나타내었다. 실험동물군의 체중은 대조군보다 높은 값을 나타내었으며 고농도 라벤더에서 가장 높은 값이 나타내었다. 실험동물군의 장기의 무게는 간과 심장을 측정하였으며 고농도 라벤더에서 가장 높은 값이 측정되었다. 결과를 통해 종지나물, 라벤더, 다시마 항산화는 항산화기능 및 모발 성장에 효과가 있다는 걸 확인할 수 있었다.