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Original Article

Aerobic exercise is an independent determinant of levels of inflammation and oxidative stress in middle-aged obese females

원문정보

Kyung-Shin Park, Brett S. Nickerson

한국운동재활학회 JER Vol.18 No.1 2022.02 pp.43-49
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초록

영어

The purpose of this study was to investigate the effects of a 4-week moderate-intensity aerobic exercise on changes of body composition and markers of inflammation and oxidative stress independent from weight loss in middle-aged obese females. Thity-five obese females were randomly assigned to either an exercise (EX, N=16) or control (CON, N=19) group. The EX performed moderate intensity aerobic ex-ercise on the treadmill for 60 min at 55% of maximal oxygen consump-tion (VO2max) for 4 weeks (3 days/wk). Body composition measurement with dual-energy x-ray absorptiometry and blood collection were con-ducted before and after the 4-weeks intervention. Blood samples were used to measure levels of tumor necrosis factor-alpha (TNF-α), C-reac-tive protein, adiponectin, total antioxidant status (TAS), and 8-hy-droxydeoxyguanosine. Four weeks of aerobic exercise intervention sig-nificantly increased VO2max in EX (P<0.001). EX also observed a decrease in TNF-α (P=0.033) and an increase in TAS (P=0.028) without changes in body weight and fat mass after 4 weeks of aerobic exercise training. No changes were observed in CON after the intervention. Results of this study indicate that moderate aerobic exercises may contribute, at least a part, to reductions of inflammation and oxidative stress inde-pendently from fat loss. Therefore, it may reduce risks of obesity-asso-ciated disorders in middle-aged obese females.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Subjects
Study design
Anthropometric measurements
Body composition assessment
VO2max test
Blood collection and analyses
Exercise intervention
Data analysis
RESULTS
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES

저자정보

  • Kyung-Shin Park Kinesiology, Texas A&M International University, Laredo, TX, USA
  • Brett S. Nickerson Kinesiology, Texas A&M International University, Laredo, TX, USA

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