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Research Article

고지방과 고콜레스테롤 식이 급여에 의해 고지혈증이 유도된 흰쥐에서 꽃송이버섯 자실체의 항고지혈증과 항비만 효과

원문정보

Anti-hyperlipidemic and anti-obesity effects of Sparassis latifolia fruiting bodies in high-fat and cholesterol-diet-induced hyperlipidemic rats

임경환, 백승아, 최재혁, 이태수

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

This study investigated the anti-hyperlipidemic and anti-obesity effects of Sparassis latifolia (S. latifolia) fruiting body powder in rats fed with a high fat and cholesterol diet (HFD). Rats were fed a normal control diet (ND), an HFD, an HFD supplemented with 5% fruiting body powder of S. latifolia (HFD+SL), or an HFD supplemented with 0.03% simvastatin (HFD+SS), for 6 weeks. The HFD group demonstrated considerable increase in body weight gain, the food efficiency ratio (FER), and plasma cholesterol and triglyceride levels, compared to the ND group. In contrast, the HFD+SL and HFD+SS groups showed significantly reduced body weight gain, food intake, and plasma cholesterol and triglyceride levels compared to the HFD group. In particular, the HFD+SL and HFD+SS diets significantly suppressed the occurrence of non-alcoholic fat deposits in the liver. Taken together, these results suggest that dietary supplementation of the fruiting body powder of S. latifolia in an HFD could lower the risks of hyperlipidemia, atherogenesis, and obesity and may be used as a functional food to manage cardiovascular disease and fecal lipid and cholesterol levels.

목차

ABSTRACT
서론
재료 및 방법
버섯 분말의 제조
실험동물의 사육 및 식이
실험 동물 식이의 제조
혈청의 분리 및 생화학적 분석
간의 조직학적 분석
분변의 총 지방과 콜레스테롤의 측정
통계처리
결과 및 고찰
체중, 식이 섭취량 및 식이 효율
혈청의 지질농도 분석
혈청의 생화학적 지표의 분석
간 지표 효소의 활성 분석
분변의 지질 및 콜레스테롤 배출 효과
간의 병리 조직학적 검사
적요
감사의 글
REFERENCES

저자정보

  • 임경환 Kyung-Hoan Im. 인천대학교 생명과학부
  • 백승아 Seung-A Baek. 인천대학교 생명과학부
  • 최재혁 Jaehyuk Choi. 인천대학교 생명과학부
  • 이태수 Tae-Soo Lee. 인천대학교 생명과학부

참고문헌

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