원문정보
초록
영어
The forensic DNA database was managed according to the °ΠAct on the Protection and Use of DNA Identification Information°π enacted in July 2010, and the integrity and accuracy of the genetic information registered in this forensic DNA database was being emphasized. In this study, we analyzed the discordance (DC) ratio for each short tandem repeat (STR) locus in 21,160 samples received from January 2016 to October 2019 in order to contribute to improving integrity and accuracy of data. In addition, we also analyzed the change in DC ratio for each STR locus after the expansion of 20 core STR locus based on Combined DNA Index System (CODIS) of the FBI laboratory in January 2018. As a result, the DC ratio for each STR locus increased from 29 cases to 67 cases according to the expansion of the STR locus, and we selected the STR loci with a high DC ratio. Also, we were able to organize the three types of DC occurrence in this study. These results suggest that may help to minimize the STR data analysis error of crime scene evidence samples and to increase the reliability of the forensic DNA database.
목차
I. 서론
II. 재료 및 방법
1. 자료의 수집
2. STR 좌위 증폭 및 분석
3. DC 발생비율 분석을 위한 STR 좌위 선정
III. 결과 및 고찰
1. STR 좌위 화장에 따른 DC 발생비율 분석
2. STR 좌위별 DC 발생비율 분석
3. STR 좌위별 DC 발생형태 분석
IV. 결론
V. 사사
VI. 참고문헌