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Original Article

Comparison of field- and laboratory-based estimates of muscle quality index between octogenarians and young older adults: an observational study

초록

영어

Muscle quality (the ratio of strength to lean muscle mass) might be a better indicator of muscle function than strength alone. Differences in muscle quality index (MQI) between octogenarians and young older adults remain unclear. The aims of the present cross-sectional study were to compare (1) MQI between octogenarians and young older adults, (2) lab versus field-based MQI tools, and (3) determine possible confounding factors affecting MQI in older adults. Compiled data from two cross-sectional studies included 175 younger and older adults (31 men and 144 women) with a mean age of 75.93±9.49 years. Participants with age ≥80 years old were defined as octogenarians (n=79) and <80 years was defined as young older adults (n=96). Laboratory MQI was derived from the ratio of grip strength to arm muscle mass (in kg) mea-sured by dual-energy x-ray absorptiometry. Field-based MQI was quan-tified from the ratio of grip strength to body mass index (BMI). Octoge-narians displayed lower field (P=0.003) and laboratory MQI (P<0.001) as compared with young older adults. There was a strong correlation effect between field MQI and laboratory MQI (P=0.001, R=0.85). BMI (P=0.001), and diabetes mellitus (P=0.001) negatively affected MQI. Women presented lower MQI (P=0.001) values than men. In light of this information, rehabilitation specialists should consider the use of field-based MQI as a tool for evaluation and follow-up of older population.

목차

Abstract
INTRODUCTION
MATERIALS AND METHODS
Study design and participants
Study 1
Study 2
Handgrip strength
Muscle quality
Body composition
Statistical analysis
RESULTS
DISCUSSION
ACKNOWLEDGMENTS
REFERENCES

저자정보

  • Dahan da Cunha Nascimento Department of Physical Education, Catholic University of Brasilia (UCB), Brasilia, Brazil, Department of Physical Education, Center University of Distrito Federal (UDF), Brasilia, Brazil, Department of Gerontology, Catholic University of Brasilia (UCB), Brasilia, Brazil
  • Jonato Prestes Department of Physical Education, Catholic University of Brasilia (UCB), Brasilia, Brazil
  • Joyce de Sousa Diniz Department of Gerontology, Catholic University of Brasilia (UCB), Brasilia, Brazil
  • Pedro Rodrigues Beal General Surgery, Hospital of São Paulo, UNIFESP-SP, São Paulo, Brazil
  • Vicente Paulo Alves Department of Gerontology, Catholic University of Brasilia (UCB), Brasilia, Brazil
  • Whitley Stone Department of School of Kinesiology Recreation and Sport, Western Kentucky University, Bowling Green, FL, USA
  • Fabiani Lage Rodrigues Beal Department of Gerontology, Catholic University of Brasilia (UCB), Brasilia, Brazil, Department of Nutrition, Health and Medicine School, Catholic University of Brasilia (UCB), Brasilia, Brazil

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