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Objectives: The aim of this study was to investigate the education status, knowledge, and perception of oral care among senior nursing students from Republic of Korea who completed all four curricular courses of Introduction to Nursing, Pediatric Nursing, Adult Nursing and Gerontological Nursing in order to provide basic data for effective oral care of inpatients. Methods: A questionnaire survey was conducted for 137 senior nursing students in the Seoul and Gangwon regions who were selected by convenience sampling. The questionnaire consisted of questions about the perception of oral care. A frequency analysis was conducted to analyze education status, perception, and general characteristics of participants. In addition, independent t-test and one-way analysis of variance were conducted to assess differences in the knowledge level according to the characteristics of the students. A p-value less than 0.05 was statistically significant. Results: The study results revealed that 63.5% of the respondents received education on oral care, with 67.8% of them receiving the education during their regular curriculum. Of the responders who said they received education, 41.4% said that education was not enough. Furthermore, the majority of respondents (56.9%) considered dental hygienists to be most suitable for the administration of oral care for inpatients. Conclusion: This study revealed nursing students’ positive perceptions of the importance of oral care and dental hygienists’performance of oral care for inpatients. Consideration should be given to healthcare workers in various professions for improving oral health in inpatients, as well as for further study of oral care in the curriculum.