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Original Article

Study on the VEGF Gene Expression and the Role of PMSG Hormone in the Development of Endometrial Cancer in Mice

초록

영어

In this study, we investigated whether infusion of colorectal cancer cell line and PMSG could increase endometrial cancer. As a result, our study confirmed that the injection of colorectal cancer can cause inflammation and cancer in the uterus and increase the VEGF gene in the uterus. The study also found that endometrial cancer was associated with PMSG.

목차

ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
Preparation and certification of animals
Animals and HCT116 cancer cell-line implantation procedure
Histological analysis of the endometrium
Immunofluorescence (IF)
RESULTS
H&E staining of mus uterus
Comparison of anatomical morphology and endometrium remodeling
Analysis of VEGF protein expression in uterus of cancer cell-injected mice
DISCUSSION
CONFLICTS OF INTEREST
AUTHOR CONTRIBUTIONS
AUTHOR’S POSITION AND ORCID NO.
REFERENCES

저자정보

  • Sang-Hwan Kim Institute of Genetic Engineering, Hankyong National University, Anseong 17579, Korea
  • Na-Hyeon Jung Major in the Animal Biotechnology, Graduate School of Future Convergence Technology, Hankyong National University, Anseong 17579, Korea
  • Min-Gee Oh Department of Animal Life Science, Hankyong National University, Anseong 17579, Korea
  • Jong-Taek Yoon Institute of Genetic Engineering, Hankyong National University, Department of Animal Life Science, Hankyong National University

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