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Review Article

The Making of a Competent Oocyte – A Review of Oocyte Development and Its Regulation

원문정보

Hammed A. Tukur, Riyadh S. Aljumaah, Ayman Abdel-Aziz Swelum, Abdullah N. Alowaimer, Islam M. Saadeldin

한국동물생명공학회(구 한국동물번식학회) Journal of Animal Reproduction and Biotechnology Volume. 35 No. 1 2020.03 pp.2-11
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초록

영어

Assisted reproductive technologies (ART) merely depend on improving the oocyte maturation and their developmental competence to produce good quality embryos. Oocyte maturation passes through long and complex molecular steps starts from the early embryonic life and ends with sperm fertilization. Oocyte developmental competence can be attained by improving the nuclear and cytoplasmic mechanisms together with some epigenetic maturation. In this review, we highlight the cornerstones of oocyte maturation on both nuclear and cytoplasmic levels. Interfering or supporting these molecular mechanisms would help in the development of novel regulating agents for reproductive performance of humans and livestock species.

목차

ABSTRACT
INTRODUCTION
THE OVARY AND FOLLICULOGENESIS
OOCYTE MATURATION, MEIOSIS AND MEIOTIC ARREST
OOCYTE MEIOTIC RESUMPTION
CYTOPLASMIC MATURATION
OOCYTE CYTOPLASMIC MOLECULAR MATURATION
EPIGENETIC MATURATION OF OOCYTES
CONCLUSION
CONFLICTS OF INTEREST
ACKNOWLEDGEMENTS
AUTHOR CONTRIBUTIONS
AUTHOR’S POSITION AND ORCID NO.
REFERENCES

키워드

저자정보

  • Hammed A. Tukur Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
  • Riyadh S. Aljumaah Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
  • Ayman Abdel-Aziz Swelum Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia, Department of Theriogenology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt
  • Abdullah N. Alowaimer Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
  • Islam M. Saadeldin Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia, 2Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt

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