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The purpose of this study is to analyze the trend of insect medicinal materials related to brain diseases in the patent. An electronic search for patents was conducted using the WIPSON database. Korea, China, Japan, USA, EU, and PCT patents, which were registered by October 4, 2019, were selected. A total of 59 patents were included in this study. Patents filed in China, Korea, Japan were 62.7%, 35.6%, and 1.7%, respectively. There was no patent filed in the USA and EU. In China, the most application was conducted after 2007. Korea had many patent applications that were submitted by research institutes and universities, but China had a high proportion of individual applicants. In IPC analysis, 86.4% of IPC were A61K, and 13.6% of IPC were A23L. Scolopendra, Scorpio, and Batryticatus Bombyx were used at high frequency for the patent. To sufficient information for utilizing patent technologies, more studies providing analyzed patent data are needed.