earticle

영어

Exercise has been realized as a highly potent treatment for a multitude of degenerative conditions including cardiovascular disease, cancer, diabetes, sarcopenia, Alzheimer’s disease and many others. These diseases are directly associated with the growth and degeneration of skeletal muscles, which is regulated by the mammalian/mechanistic target of rapamycin (mTOR) signaling pathway. Generally, mTOR activation is known to be changed by both an acute exercise and training, however the type of exercise such as resistance and endurance exercise posses different mTOR siganlaing pathways in skeletal muscles. Therefore, this review will discuss how resistance and endurance exercise activates mTOR protein in different manner in skeletal muscle cells.