원문정보
초록
영어
The main purpose of this study was to suggest a solution for inflamma-tion caused by urban daily life based on supercritical extraction of Cha-maecyparis obtusa Endl. (C. obtusa). The leaves, cone, wood, and bark of C. obtusa were separately extracted with supercritical extraction. Al-pha-pinene, anti-inflammatory active compound of C. obtusa, was ana-lyzed by electrospray ionization-mass spectrometry, gas chromatogra-phy, and gas chromatography mass spectrometry from each part of ex-tracts. As a result of the reduction rate of nitric oxide in RAW 264.7 cells, the wood extract exhibited the highest reduction rate was about 45% among extracts from four part of C. obtusa. The wood extract from C. obtusa can be developed as a good anti-inflammatory natural raw ma-terial for natural product industry.
목차
INTRODUCTION
MATERIALS AND METHODS
Supercritical fluid extraction
Fatty acid analysis
Electrospray ionization-mass spectrometry
Solid phase microextraction method
Nitric oxide assay
RESULTS
Supercritical fluid extraction
Fatty acid component
GC/MS analysis
Effects of extracts from C. obtusa and α-pinene on NO
DISCUSSION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES