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Objectives: This study was conducted to analyze the effect of hospital social responsibility(HSR) activities on organizational health and customer orientation. Methods: We conducted an online survey with hospital employees and analyzed the questionnaires of 206 selected respondents. A regression analysis was performed to determine the relationship between independent and dependent variables. Results: First, 'consumer issues', 'community involvement and development', and 'fair operating practice' factors in HSR influenced 'medical environment suitability' in organizational health. The 'fair operating practice' factor in HSR affected 'management environment suitability' and 'community orientation' in organizational health. The 'labor practices' factor in HSR affected 'practices suitability' and 'vitality' in organizational health. Second, the activities on 'consumer issues' and 'environment' in HSR have influenced 'Reliability', 'Reactivity' and 'Tangibility' in Customer Orientation. The activities on 'consumer issues' have affected 'Empathy'. Conclusions: The results of this study provide a positive direction for medical institutions as they conduct HSR activities and provide a basis for establishing effective HSR strategies.