원문정보
초록
영어
Hypochlorous acid (HOCl) is a powerful oxidant and a bactericidal agent generally produced by electrolysis, which is much more effective and safer than NaOCl. Recently mineral supplement-treated HOCL (MS-HOCl) water has received attention as a new-concept detergent due to high sterilization power, easy accessibility and safety. In this study we time-dependently investigated the physiochemical properties of MS-HOCl water depending on the kind of diluting agents (tap water, low concentration mineral water and high concentration mineral water), and confirmed anti-bacterial effect of MS-HOCl water according to the ACC level compared to electrolyzed acidic water. Weak acid electrolyzed water (EW-HOCl) was used as a positive control. We evaluated the pH, oxidation reduction potential (ORP), available chlorine concentration (ACC) and total dissolved solid particles (TDS) level to detect physiochemical properties of various kind of MS-HOCl waters. To investigate the bactericidal effects of these experimental waters, 5 different strains of aerobic and anaerobic human pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus mutans and Helicobacter pylori) were used. Three MS-HOCl waters according to ACC levels were prepared through 2-fold serial dilution, and compared with tap water, 70% ethyl alcohol and EW-HOCl. In results, MS-HOCl water had similar physiochemical properties compared to EW-HOCl water. Moreover, MS-HOCl treatment showed excellent bactericidal effect against all five human pathogenic bacterial strains compared to TW and 70% alcohol, and showed similar anti-baterial effect with EW-HOCl. Collectively, our study indicates that MS-HOCl water could be used as a efficient disinfectant alternative due to cost-effectiveness and easy accessibility in hospital settings, food process and poultry industries. However, further studies are required for its safety use.
목차
Introduction
Materials and Methods
1. Preparation of MS-HOCl water and acidic electrolyzed water (EW-HOCl),and time-dependent measurement of ACC
2. Evaluation of physiochemical properties of MS-HOCl solution according to the kind of diluting agent.
3. Evaluation of anti-bacterial effect of MS-HOCl according to the ACC level
4. Statistical Analysis
Results and Discussion
Acknowledgement
Conflict of interest
References