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논문

Anti-obesity Effect of Whole Body Vibration Exercise : A Clinical Pilot Trial

초록

영어

It is well known that exercise is effective in overcoming obesity. Recent studies have focused on various types of exercise in which vibration exercise was involved. In this study, we investigated the effect of whole body vibration (WBV) exercise using the bed-type vibrator through pre-post data analysis. Twenty participants were carefully recruited and were treated on a vibrating bed with an automatic program developed by integration of 1-8 steps for 1 hr maintaining the 40°C of bed temperature. Blood pressure, body mass indices (BMI), hematological indices, oxidative stress-related markers, cytokines, and obesity-related biomarkers such as adiponectin, resistin and irisin were measured. Results showed that diastolic blood pressure was significantly lowered after 1 hr of WBV treatment (p < 0.05). In lipid tests, total cholesterol and low-density lipoprotein cholesterol were decreased (p < 0.01, respectively). Oxidative stress-related markers such as reactive oxygen species (p < 0.05), nitric oxide (p < 0.05) and glutathione peroxidase (p < 0.01) were significantly increased. Interleukin (IL)-10, and tumor necrosis factor-α were significantly decreased and IL-6 and interferon (INF)-γ also showed decreasing trend. Adiponectin involved in insulin sensitivity was increased and resistin involved in insulin resistance decreased, but there were no significance. In addition, irisin levels were significantly decreased after the WBV exercise. In conclusion, the bed-type of WBV exercise reduced the blood pressure and cholesterol, and showed favorable response to obesity biomarkers. Also, oxidative stress level was increased but relatively stable and not severe, and inflammation and allergic reaction were not observed. Thus, the application of bed-type WBV exercise can be a safe and effective alternative for the improvement of obesity.

목차

ABSTRACT
Introduction
Materials and Methods
1. Clinical subjects
2. Experimental material
3. Experimental method
4. Oxidative stress related tests
5. Inflammation and allergic reaction responses using cytokine analysis
6. Measurement of other obesity-related markers
7. Statistical Analysis
Results
1. BMI measurement
2. WBC and biochemical indicators in blood test
3. Effect of WBV exercise on oxidative stress
4. Inflammation, allergy and
5. Obesity-related indicators
Discussion
Acknowledgment
Conflict of Interest
References

저자정보

  • Ailyn Fadriquela Department of Environmental Medical Biology, Department of Global Medical Science
  • Johny Bajgai Department of Environmental Medical Biology, Department of Global Medical Science
  • Rahima Begum Department of Environmental Medical Biology, Department of Global Medical Science
  • Jing Xingyu Department of Environmental Medical Biology, Department of Global Medical Science
  • Cheol Su Kim Department of Microbiology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea
  • Soo-Ki Kim Department of Microbiology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 26426, Republic of Korea
  • Dong Heui Kim Department of Environmental Medical Biology
  • Kyu-Jae Lee Department of Environmental Medical Biology, Institute for Poverty Alleviation and International Development, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon 26493, Republic of Korea.

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