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Objectives: The purpose of this study was to examine the state of ADHD disposition among college students and the impact of their self-esteem on ADHD in an effort to provide useful information on the prevention of ADHD in adults. Methods: A survey was conducted from April 4 to June 30, 2015, on 264 selected students at two different universities that were respectively located in the Daegu and Gyeongsan city. As for data analysis, a statistical package SPSS WIN 18.0 was employed. Results: The findings of the study were as follows: There were significant differences in overall ADHD disposition according to academic year, religion and academic standing, and self-esteem varied with gender, presence or absence of a friend of the opposite gender, academic year and academic standing. There were differences in inattention-memory problems scores, one of the sub factors of adult ADHD, according to presence or absence of a friend of the opposite gender, academic year and academic standing. Self-esteem had a negative correlation with inattention-memory (r=-0.463), hyperactivity(r=-0.269) and impulsiveness(r=-0.233). When a regression analysis was made to determine influential factors for inattention-memory, religion(β =0.121), academic standing(β=-0.153) and self-esteem(β=-0.422) were influential. Conclusions: Adult ADHD disposition and self-esteem of college students seems to be relationship. There was a positive correlation among inattention-memory, hyperactivity and impulsiveness that were three subfactors of adult ADHD.