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Background: The purpose of this study was to investigate the effects of gluteus medius strength exercise on the ankle stability of high school student with chronic ankle sprains. Methods: A total of 30 participants were divided two groups. Experimental group was 15 participants applied gluteus medius strength exercise. Control group was 15 participants performing ankle strength exercise. This study was performed for 50 minutes per day, three a week for 6 weeks. All measurements were taken to a pre and post test. Strength was measured using Power Track ll. Balance was measured using Biodex balance system for Limits of Stability and Postural Stability. Ankle Stability was measured using Cumberland Ankle Instability Tool (CAIT). Results: In the case of gluteus medius strength, there were statistically significant differences between the experimental group and the control group. For ankle stability were statistically significant differences within the experimental group according to measurements taken by Limits of Stability, Postural Stability, and CAIT. A between group comparison showed a statistically significant difference for CAIT only. Conclusion: According to our measurements it appears that gluteus medius strength training was effective in benefiting muscular strength, balance and ankle stability among the physical education.