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Purpose: The purpose of this study is to propose directions for the development of Occupational Health Nursing Intervention by identifying the current status and quality of Occupational Health Nursing Intervention Research in domestic industries. Methods: Between 2000 and August of 2018, total of 1,181 Occupational Health Nursing related published references were searched using 4 domestic databases, and of the total, 29 final theses that suited the requirements were analysed In this research, the quality assessment of literature that were selected as suitable was conducted using a tool for assessing the biasing risk of non-randomized studies, RoBANS(Risk of Biasing Assessment Tool for Non-randomized Study). Results: For all research, nonequivalent control group pre-posttest design was the most used as quasi-experimental designs. The effectiveness of intervention was found both in terms of physical and psychological aspects, and the result of the risk of biasing assessment showed a high risk levels in both “confounding variables” and “detection bias”. Conclusion: Occupational Health Nursing Intervention have been steadily making improvements in terms of both quality and quantity, and as for more effective intervention developments that improves the physical and mental health of the workers, supplementation in strict research design and in ethical aspects deems necessary.