earticle

논문검색

Poster Presentation : Gene Expression / Function

A Putative Regulator, CREBZF, May Have Roles in Reproductive Systems

원문정보

Hoon Jang, Minhwa Do, Sohyeon Moon, Minha Cho, Soojin Lee, Miseon Park, Youngsok Choi

한국동물생명공학회(구 한국동물번식학회) 발생공학 국제심포지엄 및 학술대회 2018년 한국동물번식학회, 한국수정란이식학회 공동학술대회 2018.06 pp.43-43
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

The reproductive system is very complex and diverse. Despite numerous studies, the exact mechanism of reproduction remains a subject to be explored. We have recently confirmed that the novel regulator CREBZF, which has been reported to play an important role in determining the fate of cells, is expressed specifically in the uterus, ovaries and testes, respectively. In the endometrium of uterus, CREBZF was found to be sensitively regulated by estrogen. In addition, the immunostaining showed that CREBZF is specifically expressed in the meiosis stage of spermatocyte during spermatogenesis in seminiferous tubules of testis. Finally, we discovered the strong expression of CREBZF in abnormally activated ovarian follicles by chemotherapeutic drug. These results suggest that CREBZF may play an important role in the activation of reproductive organs. In future study, we will perform the functional study and searching regulatory mechanism of CREBZF in these tissues.

저자정보

  • Hoon Jang Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Minhwa Do Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Sohyeon Moon Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Minha Cho Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Soojin Lee Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Miseon Park Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea
  • Youngsok Choi Department of Biomedical Science, CHA University, Seongnam 13496, Republic of Korea

참고문헌

자료제공 : 네이버학술정보

    함께 이용한 논문

      0개의 논문이 장바구니에 담겼습니다.