earticle

영어

Abcertin was developed as orphan drug, a new enzyme replacement therapeutic product which is imiglucerase for Gauchers patient's therapy in Korea. Glycosylation is a one of critical quality attributes for Imiglucerase. In this slide, the useful tools and approaches are shown for glycosylation analysis for imiglucerase in aspect of therapeutic protein development. And some of case study for Structure and function relation ship for glycosylation characterization will be introduced.