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PURPOSE : The purpose of this study is to compare the infection awareness level and performance of physical therapy students. METHOD : The questionnaire was distributed directly to 4th grade students in physical therapy department, and they were able to ready and reply by themselves. The questionnaire completed on the day was collected by the researcher. RESULT : As a result of examining the influence of the student’s infection awareness level on performance, the regression model was proved to be statistically significant(p<.001), and the infection cognitive level explained about 27% of the performance level. As a result of the regression coefficient significance test, the degree of infection awareness of physical therapist showed a positive(+) effect on performance (p<.001). CONCLUSION : As physical therapy students become more cognizant of infection, performance also increases. Therefore, it its necessary to educate physical therapy students to increase the awareness level of infection.