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Objectives : The purpose of this study was to verify the hypothetical models composed of elements that affect turnover intention of hospital workers. Methods : From four random hospitals, 330 questionnaires were collected. Statistical analysis was done using IBM SPSS, AMOS 22.0. Results : Self-esteem had a positive effect on intrinsic job satisfaction. Self-efficacy had a positive effect on intrinsic and extrinsic job satisfaction. Job satisfaction had a positive effect on the organizational commitment, and negative effect on the turnover intention. Organizational commitment had a negative effect on the turnover intention. Conclusions : This research found that Self-esteem and Self-efficacy affect turnover intention through Job satisfaction and organizational commitment. Therefore, we should implement policies and administration to maximize self-esteem and self-efficacy.