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The purpose of this study was to determine the effect of therapeutic ex-ercise for a woman with temporomandibular joint disorder. She was 31 year old and had limitation in the opening of mouth. When opening the mouth, she complained pain in the temporomandibular joint and noise. The health status of the patient was classified based on International Classification Functioning, Disability, and Health regarding the activity of the patient. The activity limitation was determined by the ability of opening the mouth, while the impairments in the body structure and body function were determined by the forward-headed posture due to the hypertension and shortening of upper cervical extensors. The pro-prioceptive neuromuscular facilitation (PNF) program consists of eight types of therapeutic exercises considering the alignment of the cervical spine and the pain in the temporomandibular joint. The application of the PNF program was composed of 12 sessions over 4 weeks and each session continued 30 min. Before and after the application of the PNF program, the up-down length and the left-right width of the bite mark on the apple were measured (activity limitation test). The length of the ap-ple that was bitten was measured using a tape measure (activity limita-tion test). The test on the abnormal alignment of the cervical spine was conducted using a plastic goniometer to measure the angle to the cer-vical spine (impairment test). After a 4-week PNF program, patient could open mouth wide without pain. The present results suggest that PNF program can be used to enhance the stability and mobility of the tem-poromandibular joint. With this, the impairment in the body structure and body function and activity of patient were improved.