원문정보
초록
영어
This study relates to a composition for improvement of memory or prevention and treatment of cognitive impairment using waste resources rich in beneficial substances. This study makes good effects to inhibit the activity of acetylcholinesterase in brain tissue and to improve the cognitive functions in a simulation model of cognitive impairment induced by scopolamine, so it can be available in the promotion of memory and the prevention and treatment of cognitive impairment. The composition uses the extract of fruit peels, which have long been used without causing toxicity in a wide range of food applications; therefore, it can be used safely without a risk of side effects, even in the case of a long-term administration for the preventive purpose. Furthermore, this research is a very beneficial invention in the environment-friendly aspect in association with the recycling of resources, as it is based on the novel efficacies of fruit peels, which have been conventionally disposed as a refuse of fruits due to their poor sensory qualities despite the content of beneficial substances.
목차
1. Introduction
2. Experiment Materials
2.1 Preparation of fruit peel extract
3. Experiments Method
3.1 Evaluation of inhibitory activity against acetylcholinesterase in brain tissue
3.2 Water maze test on mouse model with scopolamine-induced decline of learning and memory abilities.
3.3. Water maze test on mouse model with scopolamine-induced decline of learning and memory abilities.
4. Result and Discussion
4.1 Evaluation of inhibitory activity against acetylcholinesterase in brain tissue
4.2 Water maze test on mouse model with scopolamine-induced decline of learning and memory abilities.
5. Conclusion
References
