원문정보
초록
영어
RFW and RFE of castor fruit selected as part of the development of natural antimicrobials and antioxidants yielded 15.8% and 18.4% respectively. In the results of measuring the antimicrobial activity through paper‐disc method, the antimicrobial activity of castor fruits in ethanol extracts appeared. Especially, the activity was excellent in P. aeruginosa and S. aureus, and antimicrobial activity of C. was 1.5mm up to 16 hours. However, the proliferation of C. was observed again after 24 hours. In the MIC experiment results of RFE, S. aureus and P. aeruginosa showed 96% and 93% of antimicrobial activity, respectively. The DPPH radical scavenging activity of RLW and castor leaf ethanol extract showed 1.8±0.6% and 2.1±0.7% free radical scavenging activity at 1000(㎍/㎖). This study is expected to provide basic data for the development of antimicrobial agents and antioxidants using natural products.
한국어
천연 항균제 및 항산화제 개발의 일환으로 선택한 피마자 열매의 열수 추출물(RFW)과 에탄올 추출물(RFE)은 각각 15.8%와 18.4%의 수율을 나타냈다. Paper-disc method을 통한 항균활성 측정 결과, 피마자 열매를 에탄올로 추출한 추출물 에서 항균활성이 나타났다. 특히 녹농균 및 황색포도상구균에서 활성이 우수하였으며, 캔디다균에서도 배양 16시간까지 1.5mm 정도의 항균활성이 나타났으나 24시간 이후에는 캔디다균의 증식이 다시 관찰되었다. 피마자 열매 에탄올추출물 (RFE)의 MIC실험 결과 S. aureus와 P. aeruginosa에서 각각 96%와 93%의 항균력이 나타났다. 피마자 잎 열수추출물 (RLW)과 피마자 잎 에탄올추출물(RLE)의 DPPH radical 소거능 측정을 통한 항산화 효능 결과는 1000(㎍/㎖)에서 각각 1.8±0.6%, 2.1±0.7%의 free radical 소거율을 나타냈다. 본 연구가 향후 천연물을 이용한 항균제 및 항산화제 개발을 위한 기초 자료로 제공되리라 사료된다.
목차
요약
1. Introduction
2. Theoretical background
2.1 Ricinus communis L.
2.2 Ricin
2.3 Bacteria
3. Experiment materials and methods
3.1 Preparation of experimental materials and extracts
3.2 Experiment devices
3.3 Experimental strains and culture medium
3.4 Paper‐disc method of castor leaf and beanhot water and RFE
3.5 Minimum inhibitory concentration (MIC) measurement of castor fruits RFE
3.6 DPPH free radical scavenging experiment of castor leaves hot water and RFE
4. Results and Discussion
4.1 The paper‐disc method of castor leaves and fruits hot water and RFE
4.2 Minimum inhibitory concentration (MIC) measurement of castor fruits RFE
4.3 The results of DPPH free radical scavenging experiment of castor leaves hot water and RFE
4.4 Since parts of the castor fruits
REFERENCES