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Objectives : The purpose of this study was to analyze the effect of welfare system of medical institutions on job satisfaction and organizational commitment of female workers. Methods : A survey was performed with 556 female workers of 11 general hospital and 7 acute period hospital in Busan. Data were collected from October to November 2017 with a self-report questionnaire and analyzed using SPSS 24.0. Results : Among those aged over 40 years, high awareness of obligatory welfare, job education, free use of the annual leave, and flexible working system was a positive factor in job satisfaction. Among managers, free use of the annual leave, job education, flexible working system and child-care facilities was a positive factor in organizational commitment. Conclusions : In medical institutions with a relatively high proportion of married women, although interest in welfare for childbirth and child rearing is high, execution is sluggish, hence, policy support of government and medical institutions in this field is necessary.