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논문검색

ZEBRAFISH ANIMAL MODEL FOR HUMAN SEIZURE AND EPILEPTIC DISORDERS

원문정보

Ju Gon KIM, Jin Cheol PARK, Jeong Won BAE

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

Although epilepsy onset rate does not significantly lag behind other diseases like tuberculosis or cancer, but its patients are suffering from double torture regarding the disease because of social prejudice and point of view. For this reason, there are cases where it worsens because the person hides their disease and misses the appropriate timing for its treatment. To improve these circumstances, it is urgent to find out the onset of epilepsy and develop a new medicine to develop its remedy. Therefore, we aimed to examine if zebra fish which are similar to humans are appropriate as an animal model of epilepsy, and if so, induce epilepsy stroke and test several drugs including epilepsy medicine requested for reducing it. For the result of one of the main experiments, zebra fish showed aspects similar to humans from specific medicine related to epilepsy, and during the process of testing the epilepsy medicine based on these findings, the medicine alleviated the epilepsy symptoms when used on the zebra fish. Therefore, we were able to come to a conclusion that zebra fish is suitable as a model animal of epilepsy, and the epilepsy medicine requested for testing is appropriate as an epilepsy medicine.

목차

ABSTRACT
 1. INTRODUCTION
 2. MATERIALS AND METHODS
  1. Materials
  2. Experiment Methods
 3. RESULTS AND DISCUSSION
  1. Embryological Stages of Zebrafish
  2. Preliminary Experiments (Testing the survival rate and toxicity)
  3. Main Experiment
 4. CONCLUSION
 5. ACKNOWLEDGEMENTS
 6. REFERENCES

저자정보

  • Ju Gon KIM Dajeon science high school
  • Jin Cheol PARK Dajeon science high school
  • Jeong Won BAE Dajeon science high school

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자료제공 : 네이버학술정보

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