원문정보
초록
영어
Although epilepsy onset rate does not significantly lag behind other diseases like tuberculosis or cancer, but its patients are suffering from double torture regarding the disease because of social prejudice and point of view. For this reason, there are cases where it worsens because the person hides their disease and misses the appropriate timing for its treatment. To improve these circumstances, it is urgent to find out the onset of epilepsy and develop a new medicine to develop its remedy. Therefore, we aimed to examine if zebra fish which are similar to humans are appropriate as an animal model of epilepsy, and if so, induce epilepsy stroke and test several drugs including epilepsy medicine requested for reducing it. For the result of one of the main experiments, zebra fish showed aspects similar to humans from specific medicine related to epilepsy, and during the process of testing the epilepsy medicine based on these findings, the medicine alleviated the epilepsy symptoms when used on the zebra fish. Therefore, we were able to come to a conclusion that zebra fish is suitable as a model animal of epilepsy, and the epilepsy medicine requested for testing is appropriate as an epilepsy medicine.
목차
1. INTRODUCTION
2. MATERIALS AND METHODS
1. Materials
2. Experiment Methods
3. RESULTS AND DISCUSSION
1. Embryological Stages of Zebrafish
2. Preliminary Experiments (Testing the survival rate and toxicity)
3. Main Experiment
4. CONCLUSION
5. ACKNOWLEDGEMENTS
6. REFERENCES