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The purpose of this study was to analyze the effects of aerobic exercise and resistance exercise on body composition, complete blood count (CBC) and metabolic syndrome factors in postmenopausal women. Twenty healthy postmenopausal women composed of the step box exercise and resistance exercise group (n=10) or to a “no exercise” control group (n=10). The variables of body composition, CBC, and metabolic syndrome factors were measured in all the subjects before and after the 12-week study. Waist circumference, lean body mass and % body fat had significantly decreased, but no significantly differences in blood pressure, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and CBC in the post combined exercise group. However, individual metabolic syndrome factors were decreased compared to before combined exercise training and after combined exercise training. Our findings indicate that regular and continuous aerobic exercise and resistance exercise improves body composition, visceral fat and CBC factors. Consequently, exercise intensity and duration will be effective for preventing the immune system caused by metabolic syndrome patients in postmenopausal women.