원문정보
초록
영어
As the population ages, the life of women after menopause becomes much longer than the past, and the quality of life of old age becomes increasingly principal issue. There is a period that women experience the physical symptoms of menopause, although there are differences in degree, and the management of this period is a suitable time for women to improve their quality of life. According to the menopausal hormone therapy (MHT) and Timing Hypothesis, which has been proven in the Kronos Early Estrogen Prevention Study (KEEPS) and the Early vs Late Intervention Trial with Estradiol (ELITE) study, a relatively young woman before and after menopause can benefit from long-term beneficial effects such as prevention of osteoporosis and cardiovascular disease by early initiation of hormone therapy to alleviate menopausal symptoms. MHT should be considered for all women in healthy (without other important diseases) menopausal years, expecting to improve their quality of life through symptom relief in menopausal women and, in the long term, to prevent cardiovascular disease and osteoporosis. When applying hormone therapy to individuals, it is necessary to establish various treatment strategies according to the menopausal symptoms of individual patients (individualization of treatment) and judge the suitability of clinical application.
목차
국내 MHT 사용현황
MHT와 심혈관계 질환의 예방 효과
MHT 투여 시작 시기
MHT를 위한 estrogen 용량
MHT를 위한 progestogen 용법
MHT의 장기사용 위험성
MHT를 위한 투여기간 고찰
경구용 피임제 복용력이 있는 여성의 폐경 증상 완화를 위한 MHT로의 전환 방법과 시점
MHT를 위한 제제 선택
고찰 및 결론
감사의 말씀
참고문헌