원문정보
초록
영어
Hydrogen has been reported to relieve damage in many disease models, and is a potential additive in drinking water to provide protective effects for patients as several clinical studies revealed. Studies have demonstrated that hydrogen-dissolved water exhibits ROS-scavenging activity. In this report, we investigate the intracellular ROS scavenging and antioxidant activity of hydrogen rich alkaline water. In this study, we used hydrogen rich alkaline water (HAW) which was generated by reaction with tap water using disposable alkaline hydrogen water generator (Dr. ALKASTONE, COSTEC ECOSOO Ltd., Korea) containing natural mineral stone balls for 30 min with 20 adults. The intracellular ROS scavenging and antioxidant activity of HAW was tested by FORD test and the 2, 2-diphenyl-1- picrylhydrazyl (DPPH) assay before and after 5 min of drinking HAW (Experimental) and tap water (Control) drinking group. Our results confirm that, HAW suppresses the intracellular ROS level significantly than control group. In line, drinking HAW detect radical-scavenging activity significantly in experimental group than control group. Overall, our clinical results strongly recommended that drinking hydrogen rich alkaline water might have some promising protective effect related to oxidative stress related diseases and have an enormous impact on future healthcare system.