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Antioxidant effects of hydrogen gas inhalation for 60 mins (75ml/min) and drinking high concentration of hydrogen water (pH 8.49±0.3, ORP 23mV, hydrogen concentration 1177ppb) were examined – for more than 30 years of age of healthy 32 males volunteers. In hydrogen water drinking group, reactive oxygen species was change to 297297.0±57.9 from 303.8±53.6 in 5 mins. In hydrogen gas inhalation group, reactive oxygen species was changed to 284.4.0±53.6 from 310.4±56.2 in 60mins. Also, The individual reduction rate of reactive oxygen species was 56.3% in hydrogen water drinking group and 68.8% in hydrogen gas inhalation group. These results show that hydrogen gas inhalation and hydrogen water drinking have antioxidant effects.