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Purpose: The purpose of this study was to identify the relationship between work-related characteristics and job stressors and the factors influencing musculoskeletal symptoms of the warehouse employees. Methods: The research was a cross-sectional, descriptive study. Data were collected from 319 warehouse employees who agreed to participate in the study by using self-report questionnaires. Data were analyzed using descriptive statistics, x2-test, and logistic regression analysis (SPSS 18.0). Results: The overall prevalence of musculoskeletal symptoms was 37.6%. The logistic regression analysis revealed a posture that renders fatigue or pain, repetitive work, and a higher total score of job stressors as the risk factors for musculoskeletal symptoms in many body parts. Conclusion: Employers should plan to educate employees who work in warehouses about the correct working posture to prevent musculoskeletal diseases, stop repetitive work, and manage job stressors.