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Original Article

Physiological adaptations induced by swimming in mice fed a high fat diet

초록

영어

This study examined physiological variables of animals fed with a high-fat diet (HFD) or with a normal diet (ND) subjected to swimming at low and moderate level. Over 16 weeks, a group of animals was fed with HFD or ND, and at the 8 weeks, they started swimming with 50% or 80% of the maximum load achieved in the progressive work test. Weekly, body weight and the amount of ingested food were registered. The gly-cemic level was measured at the beginning, middle and at the end of the experiment. Adipose tissue, gastrocnemius muscles and hearts were collected for morphometry. The results showed that the animals fed an HFD had a minor caloric intake; however, the HFD increased body weight and adiposity, likely causing cardiac hypertrophy and an increase in the glycemic level. In this context, swimming with an 80% load contributed positively to weight control, adiposity, glycemic level, to control cardiac hypertrophy and induce hypertrophy in the gastroc-nemius muscle. All parameters assessed showed better results for the ND animals. Therefore, the importance of fat consumption was empha-sized in relation to obesity onset. The practice of swimming with an 80% load produced greater benefits than swimming with a 50% load for overweight treatment.

목차

Abstract
 INTRODUCTION
 MATERIALS AND METHODS
  Animals, diets, and training
  Physiological variables analyzed
  Morphometric analysis of tissues
  Statistical analysis
 RESULTS
  Variation in body weight and adiposity
  Caloric intake and glycaemia
  Progressive load test: maximum load and time of resistance
  Cross-sectional area of skeletal and cardiac fibers
 DISCUSSION
 CONFLICT OF INTEREST
 ACKNOWLEDGMENTS
 REFERENCES

저자정보

  • Pedro Augusto Silva Nogueira Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Miriam Pimenta Pereira Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Jeferson José Gomes Soares Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Anderson Ferraz Norton Filho Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Izadora Mayumi Fujinami Tanimoto Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Ivana Alice Teixeira Fonseca Federal University of Vales do Jequitinhonha and Mucuri, Minas Gerais, Brazil
  • Homero Oliveira Avelar Institute of Genetic and Biochemistry, Federal University of Uberlandia, Minas Gerais, Brazil
  • Francoise Vasconcelos Botelho Institute of Genetic and Biochemistry, Federal University of Uberlandia, Minas Gerais, Brazil
  • Leonardo Roever Department of Clinical Research University, Federal University of Uberlandia, Minas Gerais, Brazil
  • Alexandre Antônio Vieira Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil
  • Renata Graciele Zanon Institute of Biomedical Science, Federal University of Uberlandia, Minas Gerais, Brazil

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