earticle

영어

Senna tora (Cassia tora), a member of Leguminosae, is widely distributed in south-east Asian countries. The dried or roasted seed of Senna tora has been used as one of Oriental medicines for centuries for vision-improving, anti-asthenia and diuretic. Furthermore, many reports related to various biological and pharmacological activities of Senna tora have been published such as anti-inflammatory, anti-hepatotoxic, radical scavenging, anti-allergic, anti-mutagenic, antipyretic, hypoglycemic, anti-fungal and anti-bacterial effects. In this study, we have focused on characterizing and quantifying of anthraquinone compounds from Senna tora seeds during different ripening stages. Ultra-high performance liquid chromatography coupled with diode array detector and electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UHPLC-DAD-ESI-Q-TOF-MS) was used to investigate the compositional changes of anthraquinone compounds that were involved in ripening of Senna tora seeds. Furthermore, non-targeted UHPLC-ESI-Q-TOF-MS data were subjected to principal component analysis and discriminant analysis to find the potential characteristic components from different ripening stages of Senna tora seeds.