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Synthesis of glucose polymers: from laboratory to industry

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Glucose is a primary carbon source for the most of the life form of earth. Cellluose, starch, and many of polysaccharides exclusively or mainly consist of anhydroglucose. Uses of glucose polymers from maltodextrin to starch include food, paper, textile, plastics, pharmaceutical, and cosmetics industries. Recently, market size of glucose/glucose polymer is expected to show annual growth greater than 8% and expended up to 42.2 billion dollars in 2021. However, producing structurally pure glucose polymer is still a challenging task. Because, glucose polymer with degree of polymerization (DP) 100 has, literally, innumerous structures by anomeric forms (α or β) and linkage positions. To solve these problems, our research uses both in vivo and in vitro approaches. For pure maltodextrin synthesis, a pure but cheap substrate was supplied to an immobilized enzyme reactor. Polysaccharides that had different branched structure but similar DP were produced from amylopectin by purified branching enzymes. But, glycogen-like polysaccarides that are natural dendrimers were synthesized in Escherichia coli cell system and purified. These approaches still need to be improved for industrialization, but provide worthwhile methods as progress in glucose polymer synthesis.

저자정보

  • Jong-Tae Park 박종태. Department of Food Science and Technology, Chungnam National University, Daejeon 34134, Korea

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