원문정보
초록
영어
This study evaluated the physical and optical characteristics of hydrophilic ophthalmic polymer with addition of 2- methacryloyloxyethyl phosphorylcholine in the basic hydrogel ophthalmic lens material, and in particular, the utility of 2-methacryloyloxyethyl phosphorylcholine as an ophthalmic contact lens material for ophthalmologic devices was investigated. In this study 2-methacryloyloxyethyl phosphorylcholine were used as additives. For the preparation of hydrogel lens 2-hydroxyethyl methacrylate, methyl methacrylate, acrylic acid and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. The physical properties of the produced polymers were measured as followings. The refractive index of 1.433~1.393, water content of 35.95~53.16%, contact angle of 70.62~51.24o, UVB transmittance of 81.2~82.4%, UV-B transmittance of 81.2~82.4% and visible transmittance of 91.4~92.2% were obtained. Also, in case of protein absorption, the measurement showed that absorbance of Reference and MPC-10 sample was 0.2598 and 0.2250 respectively. Based on the results of this study, ophthalmic lens material containing 2- methacryloyloxyethyl phosphorylcholine is expected to be used usefully as a material for high wettability and inhibitor of protein adsorption for ophthalmic hydrogel lens.
목차
1. Introduction
2. Experimental Method
2.1. Materials
2.2. Polymerization
3. Instruments and Analysis
3.1. Physical Properties
3.2. Protein Deposit
4. Results and Discussion
4.1. Polymerization
4.2. Refractive Index
4.3. Water Content
4.4. Optical Transmittance
4.5. Wettability
4.6. Protein Absorption
5. Conclusion
Reference