earticle

영어

There is burgeoning interest in the ability to detect pro-inflammatory cytokines in response to acute exercise stress. Salivary collection is a noninvasive process and enables intensive naturalistic methodologies, such as those involving extensive repeated measures per day over time. Yet the reliability and validity of saliva-based to blood-based inflammatory biomarkers in response to stress remains unclear. I review and synthesize the published studies that have examined salivary markers of inflammation following exposure to an acute laboratory exercise stressor. Although the literature is limited, several inflammatory markers (including IL-1β, TNF-α, and IL-6) have been reliably determined from saliva and have increased significantly in response to acute exercise stress. This review suggests that specific targets may be valid and highlights specific areas of need for future research.