원문정보
초록
영어
Gelatin soft capsules, manufactured by the press through package(PTP) process, are widely used in the production of multivitamin dietary supplements and other health functional foods. Gelatin capsules can prevent light and air from having a direct contact with the contents in the capsule, and the nutrients inside the capsules are preserved without any loss. In the present study, on the basis of the results on the safety of gelatin capsules. The parameters investigated included degradation of the capsules before their shelf life, capsule deformation, and changes in specific nutrients. Moisture and heat in the production and storage environments of the capsules caused the gelatin to swell and attach some of the inorganic salts in the vitamin contents. Nutritional component analysis showed that B1, B5, B9, and B12 contents were decreased, while mineral elemental analysis shown calcium, chloride, and zinc compound were found to be infused into the gelatin of the capsule shell.
목차
Introduction
Materials and Methods
Gelatin soft capsule (GSC) and contents
GSC manufacturing process condition and notices
Thermal analysis
Non-destructive X-ray scanning
Sample preparation for component analysis by high performance liquid chromatography (HPLC)
HPLC nutritional component analysis standard and reagent
GSC morphology and mineral composition analysis
Results and Discussion
GSC damaged by moisture and heat
General analysis of degradation in damaged GSC
Thermal analysis of normal and damaged GSC
Nondestructive X-ray analysis of normal and damaged GSC
Surface morphologies of normal and damaged GSC
Loss of B group vitamins via transfer to the gelatincapsule surface
Conclusion
Acknowledgements
References