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This experiment was conducted to evaluate the effects of migration frequency on growth performance, blood profile, pork quality and economical analysis in growing-finishing pigs. A total of 56 growing pigs [(Yorkshire×Landrace)×Duroc] with an initial body weight 28.01±4.09 kg were used in this experiment. Pigs were randomly allocated to one of two treatments in a randomized complete block design and 7 replicates with 4 pigs per pen. Experimental treatments were 1) 1 site: growing- to-finishing at 1.24 m2/head, 2) 2 site: growing facility for 6 week at 0.81 m2/head followed by move to the finishing facility at 1.24 m2/head. Feeding trial was composed by two growing phase (0-3 week, 4-6 week) and two finishing phase (7-9 week, 10-12 week). As a result, different pig flows influenced on growth performance of growing-finishing pigs and 1 site treatment showed higher average daily gain, average daily feed intake, and G:F ratio on growing phase (0-6 week, p<0.01). The 2 site treatment showed higher serum cortisol level at week 6 (p=0.03). In carcass evaluation, 1 site treatment had shorter days to slaughter 110 kg body weight (p=0.01). Consequently, 1 site system had better performance and economical profits for swine farms.