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The purpose of this study was to evaluate the effects of a neuromuscular stabilization exercise on activation of muscle, kinematics, and pitching velocity. Eight males (age: 25.12±3.64 yrs) spontaneously participated in this study for 8 weeks. This study measured the muscle activation in shoulder and elbow joints, angular velocity, angular momentum, and pitching velocity of a ball, Main intervention was a neuromuscular stabilization exercise, which consisted of 10 exercises for upper limb. After the training, the muscles activation in shoulder and elbow joint were significantly increased except upper trapezius and biceps brachii (p<.05). The angular velocities in wrist and elbow joints were significantly increased after training except shoulder joint. although the displacements of wrist joints was significantly decreased after training (p<.05), In addition, pitching velocity was significantly improved after training (p<.05). Conclusively, the results of this study suggested that neuromuscular stabilization exercise may be beneficial to enhance the upper extremity muscles, throwing movements, and pitching velocity for health young males.