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Purpose: The current study (case report) seeks to examine the effects of a proprioceptive neuromuscular facilitation (PNF) exercise program on the upper extremity function and activities of daily living (ADLs) in a stroke patient. Methods: The subject was a 42 year-old woman diagnosed with right-sided hemiplegia due to stroke. Exercise therapy was provided for 50 minutes per day (5-minute warm-up, 40-minute exercise, 5-minute wrap-up) three times per week for a four-week period. The manual function test (MFT) was used to evaluate upper extremity functions. The modified Barthel index (MBI) was utilized to measure ADL. Results: After intervention using various PNF program, the MFT score increased from 23 to 26 and the MBI score increased from 62 to 66. Conclusion: After the application of the PNF program, the MFT and MBI scores increased. As compensative movement of the upper extremities declined, the movement of the upper extremities became faster and softer.