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논문검색

RESEARCH ARTICLE

야관문 추출물을 이용한 30~40대 남성의 두피 개선 효과 연구

원문정보

A Study on Effects of Lespedeza cuneata Extract on the Improvement of Scalp Conditions in Adult Men in Their 30~40s

김나연, 김주섭

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

This study conducted cytotoxicity and anti-inflammatory tests on Lespedeza cuneata extract. The study results found the followings: RAW 264.7 cells’ viability was 78%. The inhibition of production was as high as 84% at 25 ㎍/mL. It wasn’t able to confirm decrease in cytokine in pro-inflammatory mediators such as iNOS, IL- 1β and IL-6. In a protein kinase inhibition test, however, p-JNK was slightly suppressed at high concentration while p-ERK was inhibited at both low and high concentrations. Based on the results of this anti- inflammatory test, scalp tonic was produced with Lespedeza cuneata . Then, keratin, microbial biomass, erythema dose and image analyses were conducted against adult men (in their 30~40s) suffering from a scalp problem after dividing them into a control group (11 people), Lespedeza cuneata -added scalp tonic group (“T” group, 11 people) and ‘Lespedeza cuneata -added scalp tonic+scalp cleansing’ group (“TC” group, 11 people) for four weeks. First, in terms of keratin, no significant change was found in a control group while it significantly declined in T group (by 50.3%) and TC group (58.5%). In microorganism as well, no significant difference was observed in a control group. It slightly decreased in T group (63.8%, p=.066) while a significant decrease was detected in TC group (74.5%). In changes in erythema, T and TC groups decreased by 36.6% and 38.9% respectively with statistical significance. In image analysis as well, no significant difference was found in a control group while improvement of erythema was detected in both T and TC groups. Compared to a control group, therefore, scalp improvement effects were observed in T and TC groups. The anti-inflammatory effects of Lespedeza cuneata were verified. According to the said results, it appears that Lespedeza cuneata extract is considerably valuable as the material of scalp cosmetics.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 야관문 추출물 제조
  2. 세포주 및 세포 배양
  3. 항염증 측정
  4. 인체적용 시험
  5. 야관문 추출물 미스트 제형 화장품 제조
  6. 두피 측정 방법
  7. 연구윤리위원회 승인
  8. 자료 분석
 Ⅲ. 연구결과 및 고찰
  1. 야관문 추출물의 항염증 측정 결과
  2. 인체적용 시험
 Ⅳ. 결론
 참고문헌

저자정보

  • 김나연 NaYeon Kim. 건국대학교 일반대학원 생물공학과
  • 김주섭 JuSub Kim. 상지영서대학교 피부미용과

참고문헌

자료제공 : 네이버학술정보

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