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Objectives : The aim of this study was to investigate changes in job satisfaction of hospital workers according to different occupations at a university hospital in Seoul. Methods : A survey questionnaire was sent out to people working in a University Hospital in Seoul. Four hundred questionnaires were included in the final analysis. Results : The results of this study are as follows. Sense of accomplishment was a significant job satisfaction factor resulting in a high level of satisfaction. Work environment, compensation and job stability also affected job satisfaction; however, satisfaction levels appeared to be relatively low. Conclusions : When looking at the most important factors among the influencing factors that the members of the organization thought were most important for job satisfaction, the results showed that achievement, work environment, job stability and compensation were important factors.