원문정보
Five Year’s Follow-up of the Cardiovascular Disease Risk Factors among the Low Level Organic Solvent Exposure Workers
초록
영어
Purpose: The objective of the present study was to evaluate the effects of occupational exposure to low dose organic solvents on the prevalence of cardiovascular risk factors. Methods: Study design was retrospective cohort study subjected on 191 exposures and 118 controls working in a petrochemical manufacture company. The eight indicators related to CVD risk were followed up for five years from 2008 to 2012. The risk level was compared during the follow up years and subject’s characteristics, and the change of risk level were analyzed with repeated measures ANOVA and multiple logistic regression analysis. Results: At the start year 2008, the rate over cutoff value (ROCV) of BS (p<.001) and mean systolic BP (p=.017) were higher in organic solvent exposure group and the others showed no difference. And by the subject’s characteristics, odds ratio of the ROCV of BS were higher in organic solvent exposure group and work shift group as 2.51 and 3.07. Comparing the results in 2012 to those of 2008, cardiovascular disease risk in organic solvent exposure group was about 1.5 times higher than that of in the control group. Conclusion: Gradual increase in the CVD risk was identified in organic solvent exposure group. However, the risk might be influenced by shift work and bad behaviors rather than organic solvent exposure.
목차
서론
1. 연구의 필요성
연구방법
1. 연구설계
2. 연구대상 및 자료수집
3. 연구도구
4. 자료분석
연구결과
1. 일반적 특성 및 근무 특성
2. 관찰시작 연도(2008년)의 뇌·심혈관 질환 위험요인 기준치 초과율
3. 노출군의 유기용제 공기중 노출 수준 및 대사산물 농도
4. 관찰 연도와 대상자 특성에 따른 뇌·심혈관 질환 위험인자 기준치 초과율 비교
5. 공복혈당의 위험요인 수준의 관찰연도별 변화
6. 뇌·심혈관 질환 발병위험도 위험수준 분포 및 변화
논의
결론 및 제언
REFERENCES