원문정보
초록
영어
The oocyte undergoes various events during maturation and requires many substances for the maturation process. Various intracellular organelles are also involved in maturation of the oocyte. During the process glucose is essential for nuclear and cytoplasmic maturation, and adenosine triphosphate is needed for reorganization of the organelles and cytoskeleton. If mitochondrial function is lost, several developmental defects in meiotic chromosome segregation and maturation cause fertilization failure. The endoplasmic reticulum, a store for Ca2+, releases Ca2+ into the cytoplasm in response to various cellular signaling molecules. This event stimulates secretion of hormones, growth factors and antioxidants in oocyte during maturation. Also, oocyte nuclear maturation is stimulated by growth factors such as epidermal growth factor. This review summarizes roles of organelles with focus on the Golgi apparatus during maturation in oocyte.
목차
INTRODUCTION
OOCYTE MATURATION
Meiosis
Cytoplasmic Maturation
RELATION OF OOCYTE MATURATION AND GA
Effects of Epidermal Growth Factor (EGF) on Oocyte
Sec61 Beta (Sec61β)
Coatomer Subunit Protein Complex Gamma-2 (COPG2)
CONCLUSION
REFERENCES