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Background: This study was conducted to provide preventive measure for the musculoskeletal disorders in automobile parts manufacturing workers. Method: The author surveyed to the musculoskeletal symptoms prevalence and its related factors from 10th to 17th April 2011 with structured self administered questionnaires. 223 out of 225 collected questionnaires were used for final analysis, excluding 2 questionnaires with no valid response. Based on the diagnostic criteria of NIOSH (National Institute for Occupational and Health), an investigation was made into the prevalence of musculoskeletal symptoms as well as into the factors related to individual items. Results: The prevalence of musculoskeletal symptoms according to the criteria of NIOSH was the highest in the shoulder (52.9%), followed by the neck (39.%), the hand/wrist (35%), the waist (29.6%), the arm/elbow (24.7%), and the leg/food (23.8%). One-way analysis showed that among general characteristics, age was the musculoskeletal risk factor with the greatest effect. Whereas among work-related characteristics, significant risk factor didn't find. Yet it was shown that among ergonomic work postures, high degree of musculoskeletal risk was shown by the posture involving frequent and repetitive movement of the arm and the hand/wrist and also by the posture involving standing for a long time. Multiple regression analysis showed that musculoskeletal risk was 1.795 times higher in those age 50 and over than in those under age 50; 1.67 times higher in the high risk stress group than in the low risk stress group; and 1.131 higher in the group involving the repetitive use of the hand/arm than in the other groups (p<.05). Conclusion: The prevalence and stress score of automobile parts manufacturing workers were higher than other occupation workers. Among general characteristics, drinking and smoking were shown to be related to stress score; while age was shown to have significant effect on musculoskeletal risk.